This text is first of its kind as it covered the treatment as per the chronology of diseases described in Madhava Nidana. This text precisely covers the treatment part on the basis of Cikitsa Sutras (line of treatment) given in different texts. Lucid compilation is made covering the Samanya Cikitsa (general line of treatment) & Viseasa Cikitsa (general line of treatment) & Visesa Cikitsa (specific line of treatment) of all the 69 chapters of Madhava Nidana. This text will enable an emeture ayurvedic student to utilize classical ayurvedic principles in clinical practice. There is no need to search different texts to find Cikitsa Sutras. All are made available at one place. Therefore, it will be a referral text for the teachers as well as for the practitioners. Authors clinical experiences are real value addition to this work. These aspects have been incorporated where ever felt necessary. Looking at the contents of the work, the title Madhava Cikitsa Sutramala is testified.