CONTENTS:- Genetics and the Organism; Mendelian analysis; Chromosome theory of Inheritance; Extensions of Mendelian Analysis; Basic Eukaryotic chromosome mapping; Special eukaryotic chromosome mapping techniques; Gene mutation; Recombination in bacteria and their viruses; The structure, Nature and function of DNA; Introduction to recombinant DNA technology and its applications; The structure and function of Eukaryotic chromosome; Mechanisms of genetic change; The extra-nuclear genome; population genetics; Principles of plant breeding; Microbial mechanisms of Pathogenicity.
Biotechnology is the development of techniques for the application of biological processes to the production of materials of use in medicine and industry. The successful use of microorganisms in bioremediation depends on the development of a basic understanding of the genetics of a broad spectrum of microorganisms, many of them not yet isolated or studied in any detail. Microorganisms adapted to degrade specific pollutants have been found among populations growing naturally at polluted sites. However, the genetic mechanisms underlying specific adaptations are poorly understood. In the past, researchers have been unable to conduct genetic studies on these hard-to-culture organisms, but recent developments now make it possible to isolate and study genes of almost any organism. Scientists now can analyse genes that govern a wide variety of metabolic process, including the degradation of environmental pollutants. Such genetic analyses provide information about mechanisms underlying the operation and evolution of degradation pathways. The book is structured to encourage the reader to use basic scientific and biochemical engineering concepts in genetics and microbial biotechnology.