The Publication based on the survey of Sonebhadra District of Uttar Pradesh present the details of topography, climate, local medical facilities, vegetation and flora. A total number of 277 species under 68 families have been located and indentified. Commonly used Ayurvedic medicinal plant resources of 128 drugs have been identified. The position regarding the Ayurvedic drugs as minor forest produce has also been discussed. The folk medicinal practices have also been recorded. Separate appendices on Local names and Botanical names are also given.